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2021 2
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A macrophage-hepatocyte glucocorticoid receptor axis coordinates fasting ketogenesis.
Loft A, Schmidt SF, Caratti G, Stifel U, Havelund J, Sekar R, Kwon Y, Sulaj A, Chow KK, Alfaro AJ, Schwarzmayr T, Rittig N, Svart M, Tsokanos FF, Maida A, Blutke A, Feuchtinger A, Møller N, Blüher M, Nawroth P, Szendrödi J, Færgeman NJ, Zeigerer A, Tuckermann J, Herzig S. Loft A, et al. Among authors: alfaro aj. Cell Metab. 2022 Mar 1;34(3):473-486.e9. doi: 10.1016/j.cmet.2022.01.004. Epub 2022 Feb 3. Cell Metab. 2022. PMID: 35120589 Free article.
Liver-fibrosis-activated transcriptional networks govern hepatocyte reprogramming and intra-hepatic communication.
Loft A, Alfaro AJ, Schmidt SF, Pedersen FB, Terkelsen MK, Puglia M, Chow KK, Feuchtinger A, Troullinaki M, Maida A, Wolff G, Sakurai M, Berutti R, Ekim Üstünel B, Nawroth P, Ravnskjaer K, Diaz MB, Blagoev B, Herzig S. Loft A, et al. Among authors: alfaro aj. Cell Metab. 2021 Aug 3;33(8):1685-1700.e9. doi: 10.1016/j.cmet.2021.06.005. Epub 2021 Jul 7. Cell Metab. 2021. PMID: 34237252 Free article.
Orphan GPR116 mediates the insulin sensitizing effects of the hepatokine FNDC4 in adipose tissue.
Georgiadi A, Lopez-Salazar V, Merahbi RE, Karikari RA, Ma X, Mourão A, Klepac K, Bühler L, Alfaro AJ, Kaczmarek I, Linford A, Bosma M, Shilkova O, Ritvos O, Nakamura N, Hirose S, Lassi M, Teperino R, Machado J, Scheideler M, Dietrich A, Geerlof A, Feuchtinger A, Blutke A, Fischer K, Müller TD, Kessler K, Schöneberg T, Thor D, Hornemann S, Kruse M, Nawroth P, Pivovarova-Ramich O, Pfeiffer AFH, Sattler M, Blüher M, Herzig S. Georgiadi A, et al. Among authors: alfaro aj. Nat Commun. 2021 May 20;12(1):2999. doi: 10.1038/s41467-021-22579-1. Nat Commun. 2021. PMID: 34016966 Free PMC article.
Fasting-sensitive SUMO-switch on Prox1 controls hepatic cholesterol metabolism.
Alfaro AJ, Dittner C, Becker J, Loft A, Mhamane A, Maida A, Georgiadi A, Tsokanos FF, Klepac K, Molocea CE, El-Merahbi R, Motzler K, Geppert J, Karikari RA, Szendrödi J, Feuchtinger A, Hofmann S, Karaca S, Urlaub H, Berriel Diaz M, Melchior F, Herzig S. Alfaro AJ, et al. EMBO Rep. 2023 Oct 9;24(10):e55981. doi: 10.15252/embr.202255981. Epub 2023 Aug 10. EMBO Rep. 2023. PMID: 37560809 Free PMC article.